Omega 3-Optimize is the latest addition to our supplement family. It is made from extremely purified EPA and DHA in the form of triglyceride,
the most deliverable form of omega 3s. Indeed, there are two different forms of omega 3 in the market, either available in ethyl ester form (EE)
or triglyceride form (TG). They differ based on the method of esterification,
process
during which fatty acids are added to an ethanol backbone for the ethyl ester form or to a glycerol backbone for the triglyceride form.
During digestion, an enzyme (pancreatic lipase)
hydrolyses
EE to a lesser extent than TG and at a slower rate leading to higher TG bioavailability.
Our formulation displays the highest concentration
of EPA and DHA with 1000 mg per soft gel. Our product is gluten-free and contains non-GMO components. It is manufactured by
Neptune Wellness Solutions, proud member of the GOED (Global
organization for EPA and DHA omega 3s) whose focus is quality and purity of the omega 3s with strict quality and ethics standards at every
step of the production. GOED members are randomly tested and consistently pass all the requirements necessary to meet the GOED standards,
stricter than any single regulation in the world!
Omega-3 optimize is analyzed by an independent, third-party laboratory to check its purity and if all label claims are met.
Omega-3 Optimize is IFOS- 5 stars certified (highest level of certification) and you can now instantly access our certificate of analysis by scanning the QR code on the bottle!
A healthy pregnancy switches the maternal immune system toward a more tolerant, low inflammatory state. Many autoimmune diseases or other conditions such as PCOS or endometriosis may lead to systemic inflammation and oxidative stress negatively impacting oocyte/embryo quality and may be involved in infertility and recurrent pregnancy loss (RPL). Similarly, leptin (a marker of follicle hypoxia leading to oxidative stress in the oocyte) whose serum concentration is related to the amount of adipose tissue (1) can severely impact the quality of your oocyte (gamete) by disrupting:
Reduce placental inflammation when taking during the first trimester and through the pregnancy (11).
The figure below can summarize how ω3 can help reduce maternal inflammation/ oxidative stress (12).
Omega 3 fatty acid directly act on placenta to increase anti-oxidant production that will counteract the effects of reactive oxygen species (ROS).
Resolvins and protectins (products of DHA and EPA metabolism) can reduce placental PGE2 (the prostaglandin associated with parturition) and reduce placental inflammation.
Altogether, these effects can reduce the risk of pregnancy losses or complications.
Figure 1: Summary of ω3 pleiotropic effects on maternal/placental inflammation
For more information, read our blog on the topic: No benefit found with Intralipid Therapy. Ground Breaking New Study from BRI.
Minimizing paternal inflammation, improving sperm parameters (quantity and quality) and reducing sperm DNA fragmentation in male patient
Male infertility is due to low sperm production, abnormal sperm function or blockages that prevent the delivery of sperm.
A recent meta-analyze (13) involving almost 43,000 fertile men showed a dramatic decrease in the concentration of sperm of men from western countries
dropping to -52% over a 40 years period. In addition, a higher rate of sperm abnormal morphology has been widely described and is a main concern.
Regardless the potential causes that are multiple and could be attributed to obesity, stress, chemical and electromagnetic exposures, they all lead to endocrine disruption and detrimental reproductive effects such as sperm DNA damage that correlates with:
A reduction in sperm DNA damage.
For more information on how omega 3 supplement can help optimizing your semen parameters, read our blog on the topic: Dietary fish oil can positively impact sperm parameters and improve male fertility.
< Questions? Call 516.584.8710
We would be happy to help answer any questions you may have about our Omega 3-Optimize supplement
References
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Interactions of the hormones leptin, ghrelin, adiponectin, resistin, and PYY3-36
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T, Vamvakopoulos N. Serum and follicular fluid leptin levels are correlated with
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A, Tanaka T. Leptin promotes the development of mouse preimplantation
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Grant A. Randomised controlled trial of effect of fish-oil supplementation on
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Catalano PM, Hauguel-de Mouzon S. Dietary Omega-3 Fatty Acid
Supplementation Reduces Inflammation in Obese Pregnant Women: A
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e0137309.
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oxidative stress and inflammation in the placenta and maternal plasma during
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I, Pinotti R, Swan SH. Temporal trends in sperm count: a systematic review and
meta-regression analysis. Hum Reprod Update. 2017 Nov 1;23(6):646-659.
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DP. Relationship between the outcomes of assisted reproductive techniques and
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