3 miscarriages. Irreg Periods &Only DQ Alpha match found yet

liza_syca

0 Posts
Reply 3 miscarriages. Irreg Periods &Only DQ Alpha match found yet Posted on: Jan 9, 2011 at 12:17am
Dr. Braverman
I have been reading a lot about you through the forums here and other places. I need your advise on my case. I got pregnant on my own and had a m/c at 7-8 weeks and say H/b only once. Second time I got pregnant through IVf and saw one strong heartbeat and 2 sacs, m/c again at 7-8 weeks. Next time I got preg on an IUI and this time looked like blighted ovum (not sure, RE dint see hb but Obgyn said she saw it). Recently went to do immunological studies and found out that hubby has 1.2, 1.5 and I have 1.2, 1.2.
Apart from this all other results are normal. I do have very irregular periods and thts all. The RE prescribed metformin for me during the cycle.
Based on your experience and the information above, what is it that is going wrong, specially m/c always at 7-8 weeks. Is a DQ alpha match causing this? What are the symptoms of a m/c when it is because of DQ Alpha match? Is that always a an early first trimester m/c.
Thank you for your time

Liza

Dr. Braverman

2004 Posts
Re: 3 miscarriages. Irreg Periods &Only DQ Alpha match found Posted on: Jan 9, 2011 at 1:22pm
Hi Liza

Only looking at the DQalpha without looking at the remainder of the HLA genes gives me incomplete information so it is hard to comment. Miscarraige due to full HLA matching would have no differnent presentation than other miscarriages and can occur at any time from conception to late in the first tirmester after a H/B and sometimes even very late near the end of a pregnancy.
To help you I would need to see all your testing and then probably order more of my own. I would be happy to to assist you and I can order the testing for you regardless of where you live.
Please call my office and ask for Kim she will schedule a consultation for you. I look forward to speaking with you.
Dr. Jeffrey Braverman MD FACOG
Medical Director
Braverman Reproductive Immunology P.C.