Classifying/Grouping Miscarriage Type in Relation to Immunolgical Causes


1 Posts
Reply Posted on: Sep 2, 2015 at 1:44pm
Hi Dr. Braverman - I know there may not be a concrete answer - but do you have a sense of how recurrent biochemical pregnancies (more than 5 or 6) are in relation to other recurrent miscarriages or infertility? For example, are they more like recurrent implantation failure in IVF or more like first trimester miscarriages? Does it make a difference for secondary vs. primary infertiliity?

It seems to me that they are more like an implantation failure in that the immune system is preventing adequate implantation (i.e. betas never make it over 100) rather than recurrent miscarriages after the heartbeat where the immune system is attacking a fetus that was able to implant sucessfully. I would imagine that the treatment approach would be different as well. Thanks for the food for though.

Dr. Braverman

2016 Posts
RE: Classifying/Grouping Miscarriage Type in Relation to Immunolgical Causes Posted on: Sep 2, 2015 at 1:51pm
The time of the miscarriage is not as critical as is the number of losses (5 or more usually typifies loss of euploid or normal pregnancies). Also any history of losses after a fetal heart beat or of course a loss where the genetics are tested and found to be normal. The immune system can cause recurrent aneuploid losses as well, and many of these can be corrected. Some immune issues lead to early loss while others need a well developed set of cells with genetics on their surface in order to activate the immune system. Hope that helps.
Dr. Jeffrey Braverman MD FACOG
Medical Director
Braverman Reproductive Immunology P.C.