MTHFR question

Mickie

20 Posts
Reply Posted on: Mar 24, 2015 at 10:48am
Hi Dr. Braverman,

I read your email this morning that contained the article discussing MTHFR mutations and autism risk.

I tested as follows:
Compound heterozygous for MTHRF variants C677T and A1298C (this test was done in 2008).

I was prescribed and am taking Folgard RX.

Does these results severly increase the chances of autism in offspring?

Does the fact that I am taking Folgard RX help?

Thank you.

Sincerely,

Mickie

Dr. Braverman

2027 Posts
RE: MTHFR question Posted on: Mar 24, 2015 at 11:04am
I beleive that taking a methylated Folate will significantly reduce the contribution that MTFHR has towards autism. But please read the article closely(I know its very long) it mentions that just having the mutation alone is not a significant risk as most with the mutation DO NOT have a child with autism . It is pretty clear that their must be other contributing factors (most likely an underlying inflammatory or immune issue as well as a fetal predisposition ) , we are hard at work tyring to uncover these issues.
Dr. Jeffrey Braverman MD FACOG
Medical Director
Braverman Reproductive Immunology P.C.