Termination and Miscarriage

Pani

1 Posts
Reply Posted on: Aug 1, 2014 at 8:38am
Hi Dr Braverman,

I'm 36 and have been trying for a baby the last 3 years. I've had 4 fresh cycles over the last 12 months and got pregnant twice.
First time with twins that I had to terminate at 12.5 because I got infected with primary CMV that transmitted to the babies. One missed miscarriage and the other Acrania. Doctors and Virologist concluded CMV caused it and I had to terminate. This first pregnancy had no immune treatment. I have had no bleeding or spotting upto the termination.

My second pregnancy was 10 months after CMV infection and my IGM and IGG were at satisfactory levels by then. One heartbeat was found at 6 weeks, but the pregnancy ended in natural miscarriage at 9 weeks, despite immune for elevated NK cells with Intralip and steroids.
I am confused by the two outcomes of my two pregnancies and needs guidance for next steps. Can my miscarriage be linked to my termination?

For your information - I now have ten froxen blastocysts out of these 4 treatments.

I am also worried because I have silicon breast implants. They are intact and I've been told they don't cause autoimmune disease or miscarriage. But I am still worried. Should I be?

Thanks so much for any thoughts you have.

P
TTC 3 years
ME 36. DH 35.
2012: 6 cycles of Clomid
2013
ICSI 1: 1 Day 5 transferred. 2 frozen. BFN
ICSI 2: 1 Day 5 and 1 Morula transferred. BFP! Twins! pregnancy at 12 weeks due to congenital CMV virus and no survival chance for my babies.
2014
ICSI 3: 2 Day 3 transferred. BFN
IMSI 4: (NK cells treatment): 2 top quality day 5 transferred. 8 frozen. BFP. M/C 9 weeks. Not chromosome issue. More tests to come.

Dr. Braverman

2027 Posts
RE: Termination and Miscarriage Posted on: Aug 1, 2014 at 12:37pm
It appears you do have immune issues but the diagnostic testing and therefore treatment appear to be inadquate. I would be happy to help you , feel free to fill out a consult request from the website and we will schedule a free 10 minute chat to review your case.
Dr. Jeffrey Braverman MD FACOG
Medical Director
Braverman Reproductive Immunology P.C.