From Dexamethasone to Prednisolone

ThreeStars

19 Posts
Reply Posted on: Jan 3, 2015 at 3:22am
Dear Dr. Braverman,
which could argues against changing Dexamethasone to Prednisolone at aerly pregnancy (f. e. taking Dexamethasone up to 8 week of pregnancy and then Switch to Prednisone/Prednisolone for taking this until 13 week of pregnancy)?
412

Dr. Braverman

2024 Posts
RE: From Dexamethasone to Prednisolone Posted on: Jan 3, 2015 at 5:54am
I prefer to not have my pateints on Dex at all as it does cross the placenta in much greater amounts than prednisone.
Dr. Jeffrey Braverman MD FACOG
Medical Director
Braverman Reproductive Immunology P.C.

ThreeStars

19 Posts
Reply RE: From Dexamethasone to Prednisolone Posted on: Jan 13, 2015 at 12:46am
Is changing Dexamethasone to Prednisolon at 8 week of pregnancy possibile? Or which Argues against it?
412

Dr. Braverman

2024 Posts
RE: From Dexamethasone to Prednisolone Posted on: Jan 13, 2015 at 5:55am
It is possible and advisable to do so , if it is determined by your doctor that you need a steroid.
Dr. Jeffrey Braverman MD FACOG
Medical Director
Braverman Reproductive Immunology P.C.

ThreeStars

19 Posts
Reply RE: From Dexamethasone to Prednisolone Posted on: Jan 17, 2015 at 12:54am
Thank you!

Could you explain me why higher dosis of Pred or Dex are given twice daily instead once in the morning?
412

Dr. Braverman

2024 Posts
RE: From Dexamethasone to Prednisolone Posted on: Jan 17, 2015 at 6:22am
some patients find it easier to tolerate with a split dose, I dont see much difference in effect either way.
Dr. Jeffrey Braverman MD FACOG
Medical Director
Braverman Reproductive Immunology P.C.