G-CSF

Kim

3 Posts
Reply Posted on: Jun 5, 2012 at 11:49am
Dr. Braverman, I have used G-CSF uterine infusion on two occassions in the last 6 months, and both times my lining has reached a minimum of 7mm. Without the G-CSF, my linings stall at 5-6mm - typically 5mm.

I want to make sure we are covering everything, including any immune responses. Does the fact that my lining increases with the G-CSF infusion raise any concern to possible immune issues? Do you ever prescribe a prophylatic regiment (e.g. steroids, etc.) to cover any possible immune or clotting issues without testing?

Dr. Braverman

1998 Posts
RE: G-CSF Posted on: Jun 6, 2012 at 11:03am
Okay in answer to your first question , no . The increase in your lining does not mean that you have an immune issue. G-CSF simply helps to remodel the lining by recruiting in "good" natrual killer cells and causing proliferation of endometrial cells.
No I do not recommend steroids without testing as you can actually begin to impair implantation by the treatment itself if it is not warranted.
Dr. Jeffrey Braverman MD FACOG
Medical Director
Braverman Reproductive Immunology P.C.