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Infertility, IVF Failure, Egg Donation Failure and Miscarriage: the Role of Endometriosis
Please take the time to read this information. Not all the information applies to your specific case or diagnosis. The objective of this material is to familiarize you with the essential concepts of endometriosis diagnosis and its treatment.
Our approach to the diagnosis and treatment of endometriosis:
- Immunological Evaluation.
- Clinical Evaluation.
- Surgical Diagnosis and Resection.
- Combination of Medical Immune Therapy with Appropriate Fertility Treatments.
If you have failed to conceive on your own for a long period of time or if you have failed multiple IUI, IVF or even Egg Donation Cycles, silent endometriosis has to be considered as one of the possible contributing factors. Our clinical and immunological assessment includes a thorough screening for the presence of endometriosis.
Scientific evidence shows that that immune system dysfunction may be associated endometriosis and specific immunological profiles are linked to a high probability of endometriosis.
We have identified genetic markers in the HLA gene as well as cytokine and cellular markers that can suggest the presence of endometriosis even without a single symptom. This is because we now understand that endometriosis is a symptom of underlying autoimmune disease and also now recognize that the underlying disorder must be treated medically as well as surgically for optimal results.
Many doctors fail to consider the presence of endometriosis: this is particularly true in patients who only have subtle symptoms or no clinical symptoms: we call this silent endometriosis.
We have seen patients with multiple IVF failures whose doctors refuse to even consider a possible evaluation of endometriosis and continue recommending one IVF cycle after another. Although any surgery carries some risks, it is also true that repeat IVF cycles have consequences that are physical, psychological and financial. Once endometriosis is identified and treated, the appropriate fertility treatment is combined with immunological treatment.
Below you will find some useful information about endometriosis.