HLA testing and neupogen treatment

clairl

Reply Posted on: Dec 10, 2013 at 12:41pm

Dear Dr Braverman

Can neupogen treat HLA matching?

My husband and I are not matches for the DQ Alpha but have not tested beyond this.

I have all 3 KIRs missing and so planned to use Neupogen on our next IVF. Could this also treat any HLA matches? if so is it a different regime with the neupogen for treating this as opposed to treating the missing KIRs? If we are having neupogen anyway do we need to test for further HLA matches?

Many thanksClair

clair lewoski

Dr. Braverman

2026 Posts

RE: HLA testing and neupogen treatment Posted on: Dec 10, 2013 at 2:51pm

I always recommend getting the full HLA testing as well as all of the other components on our full immune panel. Missing KIR is only one small piece of information so the type fo treatment you would need or even additons you would have to make tot he neupogen can not be ascertained. Im assuming of you are using neupogen that other immune testing has been done?

Braverman Medical Team
Braverman Reproductive Immunology P.C.

clairl

3 Posts

Reply RE: HLA testing and neupogen treatment Posted on: Dec 10, 2013 at 4:04pm

Yes we've had all level 1and 2 immune tests done via Chicago lab. All came back normal
except mthfr c677t gene mutation. No killer cells in uterine lining either. My husband and I are no match on the DQ alpha test. These tests were done however pre any of my 4 ivf/ Icsi
Then very recently my husband tested positive for chlamydia and ureaplasma. I've tested negative for any of these infections.

Neupogen has been suggested to treat 3 missing KIR. LIT has been suggested for low LAD but I've never been pregnant beyond 6.5 wks nearly a year ago.

It seems we've done most tests except HLA matching? Is is this necessary given all other tests are normal?

Clair

clair lewoski

Dr. Braverman

2026 Posts

RE: HLA testing and neupogen treatment Posted on: Dec 10, 2013 at 5:48pm

I dont know what Level 1 or Level 2 denotes. There is only One set of complete immune testing that should be done I suspect you have not had this yet.

Braverman Medical Team
Braverman Reproductive Immunology P.C.

Request Your

Consultation

Click below to request a Consultation with Our Medical Team. He will review your history so that together you and he can determine your need for our services.

I'm ready to get started.

Information Center

Discussion

Forum

Join the forum to ask questions, read success stories, and stay updated on Our Medical Team's posts about new information on diagnoses and treatments.

Read Our Discussion Forum

“I express true gratitude every day for meeting Dr. B”

I worked with Dr. B's office while I cycled in Florida and with our miracle drug Neupogen, we have our little miracle, a baby girl!
“We are so Grateful!”

We came back to Dr. B after he helped us have a beautiful baby boy. We became pregnant again due to Dr. B. He is a genius and we are so grateful he was able to complete our family!
“Dr Braverman helped us achieve our dream of becoming parents.”

I cannot recommend Dr Braverman highly enough, I found him incredibly easy to work with and the distance was never an issue. My son is a true miracle and we are so thankful to Our Medical Team and his amazing team for changing our world.
“For the first time in years I felt progress. I felt my hope increasing.”

I delivered a healthy and beautiful baby boy in Jan 2013. He is ours and he is sooo precious and its all thanks to the positive support and amazing treatment Dr Braverman gave me.
“His staff is absolutely amazing and always available.”

If there is anyone contemplating working with Dr. B out of state, do not feel discouraged, he is more available then most doctors locally.
“He is a wonderful Dr who helped us achieve our dream of having a second child.”

I'm so grateful for my healthy baby girl who came a few weeks early but very healthy. She is a true miracle and I am so thankful to Our Medical Team for making this possible.
“After 4 ER's, a lap and being in 4 states we finally got our miracle!”

Diagnosis: stage 4 silent endo found with large endometrioma on ovary (surgery done In NY with one of Dr B's recommended surgeons), DOR (dx at age 28), poor egg quality and very high cytokines.
“Thank you for easing my mind”

Dr Jeffrey Braverman, I started your endo supplements and probiotics right after ovulation.
“Where do I start?!”

Where do I start?! Dr Baverman and Dr Vidali are amazing!!! They are the reason we have our little angel! To start we had a tough 3 years. 5 miscarriages and a lot of money spent let just say we had a tough ride and we didn't know how to get off it. My wife found a support group and more then one ...
“Feeling blessed and grateful, every day of my life.”

There is no way to truly thank someone who used their gift, to give you your ultimate gift. Feeling blessed and grateful, every day of my life.
“Dr. Braverman is a miracle worker!”

Dr. Braverman is a miracle worker! He is truly a caring and kind doctor who is treating woman that most other doctors have written off. I am holding my miracle 5 week old son right now thanks to Dr. Braverman. I recommend him highly!
“I hold high regard for Dr. Braverman!”

I hold high regard for Dr. Braverman, so does Liam!
“Making miracles happen!”

Making miracles happen!
“Dreams really do come true!”

One year ago on Halloween, this precious pumpkin was nestled in the pumpkin patch! We wouldn't have this amazing gift of a boy if it wasn't for Dr. Vidali and the entire team at Braverman IVF. Thank you for pushing the envelope with your work and looking beyond the standard. ...
“Miracles do happen. Yours is coming.”

I know how hard the holidays can be when you are struggling with infertility and loss, so I wanted to share a small piece of my story in case it can give you some hope during this difficult time. Both miscarriage and babies are mentioned, so if these things are triggering, please don't read on. The ...