homozygous A1298C, hypothyroidism

Marie

Reply homozygous A1298C, hypothyroidism Posted on: Aug 5, 2011 at 5:43pm

Hi Dr. Braverman,

I have just recently been diagnosed with homozygous A1298C, and also with mild hypothyroidism. I have had 5 miscarriages, one in the second trimester. Would you treat this with Lovenox? My doctors have told me that these are not clinically significant enough to cause a second trimester miscarriage and are only wanting to do high dose of folic acid and Baby aspirin since all other thrombophilia tests came back negative. Would you agree if there are no other issues that these two conditions are not enough to cause a second trimester miscarriage?

Dr. Braverman

2026 Posts

Re: homozygous A1298C, hypothyroidism Posted on: Aug 6, 2011 at 4:47am

I agree the A129 mutation is not significant, the hypothyroidism may not be the problem but if you have thryoid antibodies it could be. Also you need a full immune workup as this is most likely not thrombophilic but a classic presentation for some type of immunologic rejection. I would be happy to assist you in the workup and treatment, please call and schedule a phone consultation.

Braverman Medical Team
Braverman Reproductive Immunology P.C.

Request Your

Consultation

Click below to request a Consultation with Our Medical Team. He will review your history so that together you and he can determine your need for our services.

I'm ready to get started.

Information Center

Discussion

Forum

Join the forum to ask questions, read success stories, and stay updated on Our Medical Team's posts about new information on diagnoses and treatments.

Read Our Discussion Forum

“I express true gratitude every day for meeting Dr. B”

I worked with Dr. B's office while I cycled in Florida and with our miracle drug Neupogen, we have our little miracle, a baby girl!
“We are so Grateful!”

We came back to Dr. B after he helped us have a beautiful baby boy. We became pregnant again due to Dr. B. He is a genius and we are so grateful he was able to complete our family!
“Dr Braverman helped us achieve our dream of becoming parents.”

I cannot recommend Dr Braverman highly enough, I found him incredibly easy to work with and the distance was never an issue. My son is a true miracle and we are so thankful to Our Medical Team and his amazing team for changing our world.
“For the first time in years I felt progress. I felt my hope increasing.”

I delivered a healthy and beautiful baby boy in Jan 2013. He is ours and he is sooo precious and its all thanks to the positive support and amazing treatment Dr Braverman gave me.
“His staff is absolutely amazing and always available.”

If there is anyone contemplating working with Dr. B out of state, do not feel discouraged, he is more available then most doctors locally.
“He is a wonderful Dr who helped us achieve our dream of having a second child.”

I'm so grateful for my healthy baby girl who came a few weeks early but very healthy. She is a true miracle and I am so thankful to Our Medical Team for making this possible.
“After 4 ER's, a lap and being in 4 states we finally got our miracle!”

Diagnosis: stage 4 silent endo found with large endometrioma on ovary (surgery done In NY with one of Dr B's recommended surgeons), DOR (dx at age 28), poor egg quality and very high cytokines.
“Thank you for easing my mind”

Dr Jeffrey Braverman, I started your endo supplements and probiotics right after ovulation.
“Where do I start?!”

Where do I start?! Dr Baverman and Dr Vidali are amazing!!! They are the reason we have our little angel! To start we had a tough 3 years. 5 miscarriages and a lot of money spent let just say we had a tough ride and we didn't know how to get off it. My wife found a support group and more then one ...
“Feeling blessed and grateful, every day of my life.”

There is no way to truly thank someone who used their gift, to give you your ultimate gift. Feeling blessed and grateful, every day of my life.
“Dr. Braverman is a miracle worker!”

Dr. Braverman is a miracle worker! He is truly a caring and kind doctor who is treating woman that most other doctors have written off. I am holding my miracle 5 week old son right now thanks to Dr. Braverman. I recommend him highly!
“I hold high regard for Dr. Braverman!”

I hold high regard for Dr. Braverman, so does Liam!
“Making miracles happen!”

Making miracles happen!
“Dreams really do come true!”

One year ago on Halloween, this precious pumpkin was nestled in the pumpkin patch! We wouldn't have this amazing gift of a boy if it wasn't for Dr. Vidali and the entire team at Braverman IVF. Thank you for pushing the envelope with your work and looking beyond the standard. ...
“Miracles do happen. Yours is coming.”

I know how hard the holidays can be when you are struggling with infertility and loss, so I wanted to share a small piece of my story in case it can give you some hope during this difficult time. Both miscarriage and babies are mentioned, so if these things are triggering, please don't read on. The ...